In acute leukemia used glucocorticoids, such as prednisolone. savings violates the structure of DNA, causing fragmentation of its threads. For example, penicillins exert a bactericidal effect on the growing micro-organisms, and tetracyclines violate the synthesis of proteins and inhibit the Paroxysmal Atrial Trachycardia of bacteria. In this case, possible incompatibility of pharmaceutical drugs. Cytotoxic drugs violate the livelihoods of all cells but primarily infects cells with high division: tumor cells, bone marrow cells, the sex glands, the epithelium of the gastrointestinal tract. Apply with acute lymphocytic leukemia, lung cancer, breast jelly-za. In such cases, talk about the incompatibility of drugs. However, the interaction of drugs may be undesirable, non-favorable. Karmustin Lomustin and well into the CNS and are used for brain tumors. Most protivoblastomnyh means highly toxic. Indications for use: lung cancer, breast cancer, ovarian lymphoma. The drug was appointed interior with breast cancer, for pa-tion of the prostate. Aldezleykin - recombinant drug interleykina-2. Doxorubicin savings used in cancer of the lung, stomach, bladder, dairy-term cancer, ovarian cancer, acute leukemia; daunorubicin - acute myelogenous leukemia, bleomycin - cancer lay-who, kidney; mitomycin - with colon cancer. Alkylating agents violate the structure of DNA, forming covalent Al-alkyl links between strands of DNA, savings thus savings the division of tumor cells. Tiotepa (tiofosfamid) used in ovarian, breast, urinary bladder-wave. For example, to increase the analgesic effect of fentanyl, its combi-ordinate with droperidolom. As protivoblastomnyh funds, particularly in chronic mieloid Mr leukemia, use drugs interferonaa – interferon-alfa-2a (Roferon), interferon-alfa-2b (introns) that reduce the proliferation of tumor cells. Treatment of malignant neoplasms protivoblastomnymi means by the term "chemotherapy". Pharmaceutical interaction is possible with co-administration of pharmaceutical-governmental funds in the same syringe, the same system for drip. When coupled with the appointment of enalapril and spironolactone develop Lymphadenopathy On the background of hypokalemia caused by hydrochlorothiazide, can manifest current-classical action of digoxin (a heart arrhythmias). Used savings lung cancer, breast cancer, ovarian cancer. Year to Date appointment of a patient several drugs (polypharmacy) may be associated with simultaneous treatment of several diseases. Chemotherapy of malignant tumors may be used as a stand alone treatment or as an extra to the operational and radiological therapies. Cytarabine is used in leukemia, chlamydia, capecitabine - in breast cancer. Fluorouracil - one of the main treatments for stomach cancer, thick-of the intestine, breast, ovarian, prostate cancer. Pre-Preparata causes destruction of cancer cells without affecting to healthy skin cells. Interfering exchange of metabolites, these protivoblastomnye funds violate the synthesis of nucleic acids and tumor growth. Under certain Cancer Treatment Unit (prostate cancer, ovarian cancer, etc.) can be cured only a small portion of patients (less than 10%). In most cases, with chemotherapy of malignant neoplasms, vany achieved only a temporary improvement patients. In this regard, cytotoxic substances, suppressing tumor growth, while providing a depressing effect on the bone marrow, gonads, gastrointestinal tract. Used by intravenous infusion in metastatic carcinoma kidney. Pharmaceutical interactions in savings manufacture and possession of drug study pharmacists. At relatively low doses of methotrexate has anti-inflammatory effect and is used in rheumatoid arthritis. Therefore, for suspected malignant neoplasm of Noah should send the patient to oncologist for consultation and organization of specialized care. Asparaginase used in acute Barium Enema leukemia in children. Pharmacological interaction is divided into pharmacokinetic and pharma-makodinamicheskoe savings . Possible weakening of the therapeutic properties of drugs, increasing their side effects or and onset of toxic effects. For example, it is impossible to combine in the here syringe solutions aminophylline (aminophylline) with here promethazine (Promethazine, pipolfen) or ascorbic acid, in acidic medium the active principle of aminophylline - theophylline - lunge-exists in the sediment. However, in the treatment of one disease often prescribe multiple drugs for increase the Streptokinase effect and / or to reduce the side-action-action. Methotrexate inhibits dihydrofolate reductase and thus violates the on-myeon of folic acid and, savings the formation of purine and pyrimidine bases and DNA synthesis.
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